Itsinda ry’ubushakashatsi riyobowe na Prof XUE Tian na Prof. Ubushakashatsi bwatangajwe kumurongo mu Kagari ku ya 22 Gicurasi 2025 (EST), bugaragara mu makuru yatangajwe naItangazamakuru.
Muri kamere, imirasire ya electromagnetique iringaniye cyane, ariko ijisho ryumuntu rirashobora kubona igice gito gusa kizwi nkurumuri rugaragara, bigatuma urumuri rwa NIR rurenga impera yumutuku wikigereranyo tutagaragara.
Igishushanyo1. Imirasire ya electromagnetic hamwe nurumuri rugaragara (Ishusho yo mu itsinda rya Prof. XUE)
Muri 2019, itsinda riyobowe na Prof. XUE Tian, MA Yuqian, na HAN Gang ryageze ku ntera yatewe mu gutera inshinge za nanomateriali muri retina yinyamaswa, bituma ubushobozi bwa mbere bwo kubona amashusho ya NIR bwambaye ubusa bw’inyamabere. Ariko, kubera uburyo buke bwo guterwa inshinge za intravitreal mu bantu, imbogamizi nyamukuru kuri iri koranabuhanga ni ugushoboza abantu kumva urumuri rwa NIR binyuze muburyo budatera.
Ibikoresho byoroheje byitumanaho bikozwe muburyo bwa polymer bitanga igisubizo gishobora kwambarwa, ariko guteza imbere UCLs bihura ningorane ebyiri zingenzi: kugera kubushobozi buhanitse bwo hejuru, busaba doping yo hejuru cyane (UCNPs), no gukomeza gukorera mu mucyo. Ariko, kwinjiza nanoparticles muri polymers bihindura imitekerereze ya optique, bigatuma bigorana kuringaniza kwibanda hamwe nibisobanutse neza.
Binyuze mu guhindura isura ya UCNPs no kwerekana ibikoresho bya polymeric byangiritse-byerekana-bihujwe, abashakashatsi bakoze UCLs bagera kuri 7-9% UCNP ihuza mugihe bakomeje gukorera mu mucyo hejuru ya 90%. Byongeye kandi, UCLs yerekanye imikorere ishimishije ya optique, hydrophilicity, hamwe na biocompatibilité, hamwe nibisubizo byubushakashatsi byerekana ko moderi ya murine ndetse nabambaye abantu badashobora kumenya urumuri rwa NIR gusa ahubwo banatandukanya inshuro zigihe gito.
Igitangaje cyane, itsinda ryubushakashatsi ryateguye sisitemu yambara yindorerwamo ijisho ihujwe na UCLs hamwe nogukoresha amashusho meza kugirango tuneshe imbogamizi UCLs isanzwe iha abakoresha gusa imyumvire idahwitse yamashusho ya NIR. Iri terambere rifasha abakoresha kumenya amashusho ya NIR hamwe nuburinganire bwikigereranyo ugereranije nicyerekezo kigaragara cyumucyo, bigatuma habaho kumenya neza imiterere ya NIR igoye.
Kugira ngo turusheho guhangana n’urumuri rwinshi rwa NIR mu bidukikije, abashakashatsi basimbuye UCNPs gakondo na UCNPs ya trichromatic kugira ngo bateze imbere uburyo bwo guhuza amakuru (tUCLs), butuma abayikoresha batandukanya uburebure butatu bwa NIR kandi bakabona ibara ryinshi rya NIR. Muguhuza ibara, by'agateganyo, n'ahantu hatandukanye, tUCLs yemereye kumenyekanisha neza amakuru menshi ya NIR-yashizwemo amakuru, atanga uburyo bwiza bwo guhitamo no kurwanya-kwivanga.
Igishushanyo2. Ibara ryibara ryibishushanyo bitandukanye (indorerwamo zigereranwa zerekana indorerwamo zitandukanye) munsi yumucyo ugaragara na NIR, nkuko bigaragara muri sisitemu yambara ijisho yambara ihujwe na tUCLs. (Ishusho yo mu itsinda rya Prof. XUE)
Igishushanyo3. UCLs ituma abantu bumva urumuri rwa NIR murwego rwigihe gito, umwanya, na chromatic. (Ishusho yo mu itsinda rya Prof. XUE)
Ubu bushakashatsi bwerekanye igisubizo gishobora kwambarwa ku iyerekwa rya NIR mu bantu binyuze muri UCLs, ryatanze gihamya y’icyerekezo cy’amabara ya NIR kandi gifungura ibyifuzo bitanga umutekano mu mutekano, kurwanya impimbano, no kuvura ibitagenda neza.
Ihuza ry'impapuro:https://doi.org/10.1016/j.cell.2025.04.019
(Byanditswe na XU Yehong, SHEN Xinyi, Byahinduwe na ZHAO Zheqian)
Igihe cyo kohereza: Jun-07-2025